Vaccine Safety Roadmap

This roadmap provides recommended messaging and strategies for addressing concerns about vaccine safety. Community-based organizations, health departments, providers, and others can use these tools to promote vaccine safety in a respectful way and engage parents and patients in shared decision making.

Vaccine-Safety
In this roadmap: How can my organization address parents’ and teenagers’ concerns about vaccine safety? Tips for having conversations about vaccine safety

How can my organization address parents’ and teenagers’ concerns about vaccine safety?

Parents/caregivers and patients may have several types of questions or concerns about the safety of vaccines. Talking through vaccine safety can help parents/caregivers or patients feel more confident in choosing to immunize their child or themselves. Below, we provide resources to help address several types of common concerns:

How do I know that the ingredients in vaccines are safe?

What goes into a vaccine factsheet provides information on important ingredients that are used in vaccines.
What goes into a vaccine factsheet provides information on important ingredients that are used in vaccines.
Factsheet: What Goes Into a Vaccine? (English, Spanish)
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Graphic / Image, Document (Text)
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English, Spanish
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Factsheet details thimerosal, its use in modern vaccines and its proven safety.
Factsheet details thimerosal, its use in modern vaccines and its proven safety.
Factsheet: What Goes Into a Vaccine? Spotlight on Thimerosal (English, Spanish)
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Infographic: What Goes Into a Vaccine? Formaldehyde Spotlight. Today's vaccines use only the ingredients needed so they work and are safe. Spotlight on Formaldehyde: pronounced fr-mal-duh-hide  Why is Formaldehyde Used? Formaldehyde is used to kill the viruses and bacteria used to make vaccines, so that they can’t make people sick.  Is it safe to use? The amount of formaldehyde used in vaccines is small and “watered down.” Your body makes more formaldehyde naturally than there is in a vaccine.  Safety Check
Factsheet: What Goes Into a Vaccine? Spotlight on Formaldehyde (English, Spanish)
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Graphic / Image, Document (Text)
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Images of a lake and trees, a vial of a vaccine, the tortoise beating the hare in a race, and a mother and baby.
Factsheet: Three Important Things to Know About Aluminum and Vaccines
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English
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Factsheet: Vaccine Ingredients - What You Should Know (English, Spanish)
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Document (Text)
Race/Ethnicity:
Black/African American
Language(s):
English, Spanish
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This screenshot has text from the website giving an overview of adjuvants and vaccines.
Factsheet: Adjuvants and Vaccine Safety
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Website
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English
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Talking Points: Here’s Why We Know COVID-19 Vaccine Ingredients Are Safe (English, Spanish)
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How are vaccines made and tested for safety?

Video still shows text against a blue patterned background.
Social Media: Video Outlines the Steps of Developing and Approving a Vaccine (English, Spanish) (0:42)
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Multiple Races/Ethnicities
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Factsheet: Vaccine Safety Infographic (English, Russian, Spanish, Ukrainian)
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Language(s):
English, Russian, Spanish, Ukrainian
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First page of PDF factsheet
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Factsheet and Graphics: The Process for Developing Safe and Effective Vaccines (English, Spanish)
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English, Spanish
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Image of a Black woman holding her forehead with her eyes closed
Social Media: Video Highlights That Vaccines are Tested (English, Spanish) (0:22)
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Video
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Multiple Races/Ethnicities
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English, Spanish
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Factsheet: Developing Safe Vaccines (English, Dari, Kinyarwanda, Pashto, Swahili, Ukrainian)
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Document (Text)
Language(s):
English, Dari, Kinyarwanda, Pashto, Swahili, Ukrainian
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CDC webpage
Factsheet: Developing Safe and Effective Vaccines
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Website
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English
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Image of an Asian woman with gloves holding a test tube
Video: How Are Vaccines Tested Before They Can Be Given to Kids? (2:08)
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Video
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English
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How do I know vaccines will not cause serious side effects?

a thermometer and bandaid and text "why does my child get a fever... after getting vaccinated?
Video: Why Does My Child Get a Fever After Getting Vaccinated? (English, Spanish, Dari) (0:45)
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Video
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Dari, English, Spanish
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Social Media: Graphic on the Benefits vs. Risks of COVID-19 Vaccines (English, Spanish)
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English, Spanish
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Graphic of two Latina women facing each other while sitting down, one is holding a baby that is sleeping, and there is a circular bubble with a close up of the baby's face
Video: Vaccine Worries - Dispelling Myths and Embracing Safety (1:14)
Format:
Video
Race/Ethnicity:
Hispanic, Latinx, Latino, Latina
Language(s):
English
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Image of an older Black man smiling and embracing a Black woman
Video: COVID-19 Vaccines are Safe and Side Effects are Normal (0:24) (English, 44 Languages)
Format:
Video
Race/Ethnicity:
Asian, Black/African American, Hispanic, Latinx, Latino, Latina, Middle Eastern, Multiple Races/Ethnicities, Pacific Islander
Language(s):
Afar, Amharic, Arabic, Burmese, Cantonese, Chin Hakha, Chinese, Dari, Dinka, English, Farsi, French, Haitian Creole, Hmong, Karen, Karenni, Kinyarwanda, Korean, Lao, Lingala, Mam, Mandarin, Marshallese, Mixteco, Nepali, Oromo, Pashto, Popti', Portuguese , Q'anjob'al, Rohingya, Russian, Sango, Sinhala, Somali, Spanish, Swahili, Tagalog, Tamil, Telugu, Tigrinya, Ukrainian, Urdu, Vietnamese
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Top right: a woman gets an adhesive bandage placed on her shoulder. Bottom left: A woman speaks with a female healthcare provider. Text reads, "Another study confirms COVID-19 vaccines are safe. New data shows no association between mRNA vaccines and cardiac death."
Social Media: Graphic Emphasizes that COVID-19 Vaccines Are Safe For Your Heart (English, Spanish)
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Graphic / Image
Race/Ethnicity:
Multiple Races/Ethnicities
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English, Spanish
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Search box text reads, "Will My Child’s Future Fertility Be Affected by the COVID Vaccine?"
Video: Will My Child’s Future Fertility Be Affected by the COVID Vaccine? (0:41)
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Video
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English
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How does the Vaccine Adverse Event Reporting System work?

Image of an elderly Black man doctor giving a vaccine card to a white woman patient
Video: How VAERS Works to Ensure Vaccine Safety (2:04)
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Video
Race/Ethnicity:
Multiple Races/Ethnicities
Language(s):
English
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A four-part carousel post shows people of different races and gender expressions looking and pointing at iPads and computer screens. They include doctors and scientists in white coats along with people in every day clothing. Some people look pensive, while others are smiling. The carousel text is displayed on bright colorful shapes overlaid on the images.
Social Media: Graphics Explain the Vaccine Adverse Event Reporting System (English, Spanish)
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Graphic / Image
Race/Ethnicity:
Multiple Races/Ethnicities
Language(s):
English, Spanish
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Image includes cartoon images of an elderly white women with her daughter and of a Black pregnant woman speaking with a woman doctor
Factsheet: Proof That Vaccine Monitoring Works (English, Spanish)
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Document (Text)
Race/Ethnicity:
Multiple Races/Ethnicities
Language(s):
English, Spanish
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Are new types of vaccines, such as mRNA vaccines for COVID-19, less safe?

A Hispanic/Latina girl rolls up her sleeve to show an adhesive bandage on her arm. Text reads, "Just a reminder: Our mRNA vaccines are safe and provide valuable protection against COVID-19."
Social Media: Graphic Highlights the Safety of mRNA Vaccines (English, Spanish)
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English, Spanish
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Cartoon image of a person sweating surrounded by magnified cartoon virus, mRNA, and the vaccine explaining how they all interact to build antibodies. The CDC logo is at the bottom.
Factsheet: How mRNA COVID-19 Vaccines Work (English, Spanish)
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English, Spanish
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Video still shows a Black woman smiling down at the band aid on her arm after getting vaccinated, a Black mother holding her son and someone rolling up their sleeve preparing to receive the vaccine.
Social Media: Video Highlights the Lifesaving Science Behind mRNA Vaccines (English, Spanish) (0:21)
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Video
Race/Ethnicity:
Multiple Races/Ethnicities
Language(s):
English, Spanish
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Do vaccines cause autism in children?

A Black man next to images of an apple and a child's building block
Video: The Truth About Vaccines and Autism (English, Spanish, Dari) (2:57)
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Video
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Dari, English, Spanish
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Social Media: Video Indicates No Link Between Vaccines and Autism (English, Spanish) (1:01)
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English, Spanish
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Image with five panels including text about research confirming no link between vaccines and autism.
Social Media: Graphics Detail Evidence That Vaccines Do Not Cause Autism (English, Spanish)
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Factsheet shows cartoon images of a megaphone, brain and scientist looking into a microscope.
Factsheet: How We Know There's No Link Between Vaccines and Autism (English, Spanish)
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Document (Text)
Language(s):
English, Spanish
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Children's Hospital of Philidelphia webpage
Toolkit: MMR Vaccine and Autism
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Video, Document (Text), Website
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English, Spanish
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Talking Points and FAQs: How We Know There’s No Link Between Vaccines and Autism (English, Spanish)
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English, Spanish
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Factsheet: Vaccines & Autism - What You Should Know (English, Spanish)
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English
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Video: Do Vaccines Cause Autism? (2:05)
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Is it safe for children to get multiple vaccines at once?

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Factsheet: Too Many Vaccines? What You Should Know (English, Spanish)
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Factsheet: Information for Parents About Children Getting Multiple Vaccines at One Time
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Image shows the speaker in the video, a White woman wearing glasses, and a banner at the bottom of the image with her title: Alice Sato, MD, PhD
Video: Is It Safe to Get Multiple Vaccines at Once? (1:20)
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Graphic shows a Black female pediatrician smiling.
Video: Is It Okay for Teenagers to Get Several Vaccines at Once? (1:10)
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Factsheet: Multiple Vaccines at Once
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What are the benefits of vaccinating my child?

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Talking Points and FAQs: Routine Vaccines Keep Kids Safe (English, Spanish)
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Language(s):
English, Spanish
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text can't my child get immunity from having an infection? with an image of a virus
Video: Why Vaccines Are Safer Than Natural Immunity (English, Spanish, Dari) (0:45)
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Video
Language(s):
Dari, English, Spanish
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Image with six panels, first of a white girl getting a vaccine shot, second of animations of a man, woman, and baby's face, third of a Black man sitting next to a white boy child, fourth of a white woman in a school setting with other children, fifth of a conversation bubble with a plus sign, sixth of a conversation bubble with a question mark
Social Media: Graphics Communicate the Importance of Pediatric Vaccines
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Graphic / Image
Race/Ethnicity:
Multiple Races/Ethnicities
Language(s):
English, Spanish
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Graphic shows an image of a bike with training wheels and helmet along with an image of two young children together.
Social Media: Graphic Compares Seat Belts and Bike Helmets to Children's Vaccines (English, Spanish)
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English, Spanish
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Image shows a cartoon of a Latina woman with her baby sitting across from a Latina woman who is a healthcare provider.
Video: Routine Vaccination Schedule - Why All The Doses Are Important (1:30)
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Video
Race/Ethnicity:
Hispanic, Latinx, Latino, Latina
Language(s):
English
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Graphic shows an Asian woman talking about vaccines from her perspective as a pediatrician
Video: The Importance of Childhood Vaccinations (2:02)
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Video
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Additional vaccine safety resources

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Report: Plain Talk About Immunizations (English, Spanish)
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Language(s):
English, Spanish
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Factsheet: Vaccine Safety - What You Should Know (English, Spanish)
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Document (Text)
Language(s):
English, Spanish
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Image of a white family gathering and smiling at the park
Report: Vaccine Safety and Your Family - Separating Fact From Fiction (English, Spanish)
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Document (Text)
Language(s):
English, Spanish
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factsheet called childhood vaccinations Top 12 questions answered with the nuance you're looking for
Talking Points and FAQs: Answers to 12 Questions on Childhood Vaccinations
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Document (Text)
Language(s):
English
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healthychildren.org website
Factsheet: Frequently Asked Questions From Parents on Vaccines
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Website
Language(s):
English
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johns hopkins school of public health webpage
Tool: Interactive Guide to Routine Vaccinations (English, Spanish)
Format:
Video, Website
Race/Ethnicity:
Multiple Races/Ethnicities
Language(s):
English, Spanish
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Graphic shows the first page of the factsheet and an image of a young girl reading a book in a library. Text says: Vaccine Safety: Examine the Evidence.
Factsheet: Vaccine Safety - Examine the Evidence
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Website
Language(s):
English
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colorful comic book cover with several differently abled children
Toolkit: Ultra Germ Fighters Activity Book (English, 22 Languages)
Format:
Document (Text)
Race/Ethnicity:
Multiple Races/Ethnicities
Language(s):
English, Amharic, Arabic, Simplified Chinese, Traditional Chinese, Dari, French, Khmer, Korean, Marshallese, Mixteco, Oromo, Pashto, Russian, Samoan, Somali, Spanish, Swahili, Tagalog, Tigrinya, Tongan, Ukrainian, Vietnamese
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Tips for having conversations about vaccine safety

The following section provides tips for talking with people who are hesitant about vaccines. Even when presented with factual information about vaccine safety, people may not trust that information. 


Some populations have both lived experiences and historical experiences that predispose them to distrust government and institutional involvement in their health. It is important to acknowledge that when talking about vaccine safety. Engaging trusted messengers can help you effectively engage audiences who may have lower trust in the medical system.

How can my organization engage and equip trusted messengers?

Trusted messengers are individuals or organizations who are highly trusted by their communities to act a as credible source of vaccine safety information. These could include community health workers/promotores, health providers (especially those who are multilingual), faith leaders, and local figures or celebrities. Engaging trusted messengers to communicate vaccine safety information can help those messages resonate.

Cover page of PDF toolkit displays title text and the image of a brain overlaid a heart.
Toolkit: Building Confidence as a Trusted Messenger of Health Information
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Toolkit: Increasing Vaccinations through Trusted Messengers
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Race/Ethnicity:
Hispanic, Latinx, Latino, Latina
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English
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report title page
Webinar: Faith-Based Outreach for COVID-19 and Beyond
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Document (Text), Website
Race/Ethnicity:
Multiple Races/Ethnicities
Language(s):
English
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How have other organizations addressed community members' concerns about vaccine safety?

This section provides examples of how other organizations have addressed concerns about vaccine safety or addressed hesitancy more broadly in real life outreach. Below, we provide additional resources that may be useful in planning such outreach:

MP3 player shows options play, fast forward, and rewind options for recording. Above the control bar is an image of a blue wave with the words "critical value: an urban institute podcast" within the image
Podcast: Critical Value Episode: How to Build Vaccine Confidence Across Communities (24:12)
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Audio
Race/Ethnicity:
Black/African American, Hispanic, Latinx, Latino, Latina
Language(s):
English
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Webinar: How to Mount a Successful Flu Campaign - Lessons From the Big Easy
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English
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Report: Flu and COVID-19 Immunization Outreach Action Summary
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English
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webinar slide showing a Latina woman and Muslim man who will be presenting during the webinar
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Webinar: Collaborating with Faith Leaders to Build Vaccine Confidence (English, Spanish)
Format:
Video, Document (Text)
Race/Ethnicity:
Multiple Races/Ethnicities
Language(s):
English, Spanish
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